An estimated 105-106 DNA lesions are generated in the human genome daily. The human genome is constantly being assaulted by various sources of DNA damage, which threaten DNA stability and integrity.

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

DNA is well known as the blueprint of life, necessary for an organism to facilitate living processes. DNA can be damaged by various factors such as radical metabolites, radiation, and some toxic ...

Combining an optical tweezer technology called C-trap that manipulates a single molecule of DNA and a novel approach, researchers were able to receive a detailed view into how cells find and repair ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...

A novel technology combined with optical tweezer C-trap technology gives researchers new insight into DNA repair mechanisms. Researchers at the University of Pittsburgh (PA, USA) have developed a ...

A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital role in safeguarding the most vulnerable areas of DNA. By forming ...

In a recent study published in the journal Nature, researchers found that the recruitment of neurons to memory circuits is preceded by a cascade of molecular events induced during learning, which ...

A team at Harvard Medical School has identified a novel mechanism of DNA repair that occurs exclusively in neurons, which are some of the longest-lived cells in the body. The research, conducted in ...